Submit project

Fo consider the project complete the form. Private and contact information will hidden.
Your name
Your Email
Project title
Project amount
Project description
Please, be as precise as possible in your descriptions. This will help to avoid misunderstandings and unnecessary clarifications.

Bioengineering Rehabilitation for Wounded

Gene involved in healing fractures opened

A team of scientists from Lawrence Livermore National Laboratory (LLNL) in the US have identified a gene regulator of stem cells are involved in the healing of fractures. The discovery will help to develop new therapeutic treatments for injuries that are difficult to treat. Results of the research have been published in the “The Bone Journal”.
Regeneration of fractures involves the healing of bones, muscles, blood vessels and the thin shell of bone (periosteum). The periosteum contains stem cells that migrate to the site of injury and differentiate into chondrocytes (cartilage forming) or osteoblasts (bone forming).

To this day the interaction between stem cells and periosteum cells in the treatment of bone fractures has been little studied. The team of scientists from LLNL and Indiana University, opened Sostdc1 – gene regulator of stem cell activity in the recovery of fractures. The study showed that Sostdc1 plays a critical role in self-renewal and differentiation of stem cells that can be used in the development of new therapeutics for fractures that are difficult to treat.
There are two types of bone: cortical – dense and hard tissue that acts as the outer layer of most bones; and spongy, which is located at the ends of long bones near the joints and in the vertebrae.

The study found that mutant mice lacking the gene Sostdc1, despite lower trabecular bone density had thicker and more dense cortical layer of bone, which was restored after changing in less time compared to genetically normal counterparts.
In addition, the researchers showed that gene suppression of Sostdc1 induces a proliferation of stem cell populations and their migration to the site of injury, accelerating regeneration.
Earlier studies have found a gene involved in embryo implantation of Sostdc1, led to the formation of teeth and hair follicles and in the development of kidney disease progression and cancer.
“Our work describes previously unstudied gene function Sostdc1, emphasizing its potential role in metabolism and restoring the skeleton,” Gaby Loots, LLNL biologist and lead author of the article, said.

The study showed that Sostdc1 plays an important role in the shaping and the restoration of the spongy bone in the early stages of recovery after crisis, and its absence affects the behavior of stem cells in response to injury.
“Our research will further improve the performance of stem cells in other tissues,” LLNL biologist Nicole Collette, first author of the paper, said.

Earlier, The People’s Project reported the incredible restoration of the bone in a 19-year-old’s leg. Recently doctors formed new bone in a wounded soldier from the “Donbas” Battalion.

In the project Bioengineering Rehabilitation for Wounded, iLaya clinic doctors are using the latest biotechnology restore the damaged limbs of wounded Ukrainian soldiers.

Currently the collection of funds for the treatment of five wounded is underway and four more are waiting in line to join the project. For them biotechnology represents their only chance for recovery. Since the state, through legislative and other restrictions, can not support biotechnology in the treatment of wounded soldiers, their only hope lies with people.

We ask you to get involved and help Ukraine’s defenders.

Donate to other projects
Founds raised Treatment continues

Bioengineering Rehabilitation for Wounded

Regeneration of bone and tissue loss, sustained through mechanical or gunshot wounds through application of ilaya.regeneration stem cell technology

30 520 391 UAH (834 606 USD) needed
100% raised
Read more
Реквізити ПриватБанку для переказу у гривнях
Миколаївський обласний благодійний фонд “РЕГІОНАЛЬНИЙ ФОНД БЛАГОЧЕСТЯ”
ПАО КБ ПриватБанк
ЄДРПОУ: 36143302
МФО: 305299
IBAN-код:
Призначення платежу: Благодійний внесок. “”
USD
Beneficiary: Mykolayiv Regional Charitable Foundation “Regional Foundation Blagochestya”
IBANcode: UA583052990000026007011702069
Beneficiary address: UA 54000, Mykolaiv, Buznyka str. 5, 118
Beneficiary bank: Privatbank
50, Naberezhna Peremogy Street, Dnipropetrovsk, 49094, Ukraine
Swift code: PBANUA2X

Intermediary bank: JP Morgan Chase Bank,New York ,USA
Swift code: CHASUS33
Correspondent account: 001-1-000080
Description: Charitable donation for ‘’ project
or
Intermediary bank: The Bank of New York Mellon, New York, USA
Swift code: IRVT US 3N
Correspondent account: 890-0085-754
Description: Charitable donation for ‘’ project
EUR
Beneficiary: Mykolayiv Regional Charitable Foundation “Regional Foundation Blagochestya”
IBANcode: UA703052990000026002041702959
Beneficiary address: UA 54000, Mykolaiv, Buznyka str. 5, 118
Beneficiary bank: Privatbank
50, Naberezhna Peremogy Street, Dnipropetrovsk, 49094, Ukraine
Swift code: PBANUA2X

Intermediary bank: Commerzbank AG ,Frankfurt am Main, Germany
Swift code: COBADEFF
Correspondent account: 400886700401
Description: Charitable donation for ‘’ project
PLZ
Beneficiary: Mykolayiv Regional Charitable Foundation "Regional Foundation Blagochestya"
IBAN Code: UA363052990000026006001705679
Name of the bank: JSC CB "PRIVATBANK", 1D HRUSHEVSKOHO STR., KYIV, 01001, UKRAINE
Bank SWIFT Code: PBANUA2X
Beneficiary address: UA 54000, Mykolaiv, Buznyka str. 5, 118
CORRESPONDENT BANK: Bank Pekao/Grupa Pekao S.A., Warsaw, Poland
Account in the correspondent bank: PL13124000013140533111120301
SWIFT Code of the correspondent bank: PKOPPLPW
Description: Charitable donation for "" project.
GBP
Beneficiary: Mykolayiv Regional Charitable Foundation “Regional Foundation Blagochestya”
IBANcode: UA583052990000026007011702069
Beneficiary address: UA 54000, Mykolaiv, Buznyka str. 5, 118
Beneficiary bank: Privatbank
50, Naberezhna Peremogy Street, Dnipropetrovsk, 49094, Ukraine
Swift code: PBANUA2X

Intermediary bank: JP Morgan Chase Bank,New York ,USA
Swift code: CHASUS33
Correspondent account: 001-1-000080
Description: Charitable donation for ‘’ project
or
Intermediary bank: The Bank of New York Mellon, New York, USA
Swift code: IRVT US 3N
Correspondent account: 890-0085-754
Description: Charitable donation for ‘’ project

Press about us

Partners