Bioengineering Rehabilitation for Wounded

June 21, 2016

Antibiotics can prevent transplant donor stem cells

Antibiotics can prevent transplant donor stem cells

Broad-spectrum antibiotics can destroy the intestinal microflora, adversely affecting the transplantation of allogeneic (donor) stem cells.
These are the results of a recent study involving 857 patients, published in Science Translational Medicine.
According to scientists, the “good” bacteria protect against the development of graft-versus-host reaction (RTPH) that occurs when transplanting genetically non-identical donor cells through the activity of the immune system of the recipient. Antibiotics in this case can harm. On the other hand, transplant patients are vulnerable to deadly bacterial infections and require broad spectrum treatment
To better understand the impact of antibiotics on the risk of RTPH and the success of stem cell transplantation Yusuke Shono, Melissa Docampo and colleagues analyzed 857 medical records of patients who underwent transplantation of allogeneic hematopoietic cells. Scientists compared the names and doses of antibiotics to cases of complications.
In addition, to the authors, samples of feces were available, which can determine the microbial diversity of the intestinal microflora each patient after treatment with antibiotics. Additional experiments were conducted with stem cell transplantation in mice who were given broad-spectrum antibiotics.
Experiments have confirmed that this antibiotic, which scientists compared to carpet bombing, often leads to RTPH. Although the work of Dr Shono is preliminary and requires serious verification, some experts believe that it is “very alarming”, which should not be ignored by doctors.
Source: http://stm.sciencemag.org/content/8/339/339ra71

In the Bioengineering Rehabiliation for Wounded project, iLaya clinic doctors are using the latest biotechnology to restore the damaged limbs of military personnel. Currently, the ongoing project is raising funds to treat two wounded, about five additional wounded are waiting in the queue to join the project. For them, biotechnology is the only chance they have to return to a healthy life. Please join the project and support Ukraine’s defenders.

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Altogether on the project

Bioengineering Rehabilitation for Wounded

15643 people

donated

30 149 130 UAH (1 090 974 USD)

of 30 520 391 UAH (1 104 408 USD) needed

98% raised

Updated 27.12.2018 at 16:56
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save live & ilaya and mykolaiv fond eng

Requisites of the project Bioengineering Rehabilitation for Wounded

PrivatBank for UAH transfers

Mykolaiv regional charitable foundation “BLAGOCHESTYA REGIONAL FUND”
PC CB PrivatBank
USREOU: 36143302
MFO: 326610
Account: 26004053210825
Purpose of payment: charity donation. Bioengineering rehabilitation for wounded

SWIFT-transfer in USD

Beneficiary: Mykolayiv Regional Charitable Foundation “Regional Foundation Blagochestya”
IBAN­code: UA803266100000026009053209659
Account: 26009053209659
Beneficiary address: UA 54000, Mykolaiv, Buznyka str. 5, 118
Beneficiary bank: Privatbank
50, Naberezhna Peremogy Street, Dnipropetrovsk, 49094, Ukraine
Swift code: PBANUA2X

Intermediary bank: JP Morgan Chase Bank,New York ,USA
Swift code: CHASUS33
Correspondent account: 001-­1­-000080
Description: Charitable donation for ‘Bioengineering rehabilitation for wounded’ project.
or
Intermediary bank: The Bank of New York Mellon, New York, USA
Swift code: IRVT US 3N
Correspondent account: 890-­0085-­754
Description: Charitable donation for ‘Bioengineering rehabilitation for wounded’ project.

SWIFT-transfer in EUR

Beneficiary: Mykolayiv Regional Charitable Foundation “Regional Foundation Blagochestya”
IBAN­code: UA413266100000026009053206287
Account: 26009053206287
Beneficiary address: UA 54000, Mykolaiv, Buznyka str. 5, 118
Beneficiary bank: Privatbank
50, Naberezhna Peremogy Street, Dnipropetrovsk, 49094, Ukraine
Swift code: PBANUA2X

Intermediary bank: Commerzbank AG ,Frankfurt am Main, Germany
Swift code: COBADEFF
Correspondent account: 400886700401
Description: Charitable donation for ‘Bioengineering rehabilitation for wounded’ project.


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