Bioengineering Rehabilitation for Wounded

July 26, 2016

Mutation associated with multiple sclerosis revealed

Mutation associated with multiple sclerosis revealed

The risk of multiple sclerosis may be associated with the presence of rare mutations in the genome that affect the gene NR1H3, this question is posed in this article published on the website “Live Science”. People with the mutation suffer a rapidly progressive form of multiple sclerosis at a rate of 70% more than those where this mutation is absent.

The mutation is quite rare – only one patient with multiple sclerosis per thousand, but it will help identify to possibly predict the risk of serious illness in other family members, as well as for the timely diagnosis of people at risk, they can then begin treatment in the early stages and slow the disease’s progression.

Most patients suffer from a form of multiple sclerosis in which the acute phase changes to a period of remission, but 10-15% are diagnosed with primary progressive multiple sclerosis. The status of these patients only deteriorates, worsens, does not go into remission and symptoms increase.
Previously, researchers could not identify which genes might be responsible for the occurrence of multiple sclerosis, although noticed that the disease often occurred in families.

During the experiment, scientists from the University of British Columbia examined the genomes of members of a Canadian family across two generations in which five people were ill with progressive multiple sclerosis. The specialists were able to identify mutations affecting the gene NR1H3. In addition, they analyzed data on 2000 patients with multiple sclerosis and found the mutation in one family.

However, the researchers also found the mutation in some people who were healthy and had no signs of disease. This indicates that the mutation only increases the risk of multiple sclerosis, but is not the direct cause of its development.
Based on the data, scientists plan to create an animal model, which will examine the development of the disease and garner more knowledge of new methods of dealing with the disease.

Earlier, The People’s Project reported the incredible restoration of the bone in a 19-year-old’s leg. Recently doctors formed new bone in a wounded soldier from the “Donbas” Battalion.

In the project Bioengineering Rehabilitation for Wounded, iLaya clinic doctors are using the latest biotechnology restore the damaged limbs of wounded Ukrainian soldiers.

Currently the collection of funds for the treatment of six wounded is underway and four more are waiting in line to join the project. For them biotechnology represents their only chance for recovery. Since the state, through legislative and other restrictions, can not support biotechnology in the treatment of wounded soldiers, their only hope lies with people.

We ask you to get involved and help Ukraine’s defenders.

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Altogether on the project

Bioengineering Rehabilitation for Wounded

15508 people

donated

30 015 455 UAH (1 086 137 USD)

of 30 441 922 UAH (1 101 568 USD) needed

98% raised

Updated 27.12.2018 at 16:56
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Project manager

save live & ilaya and mykolaiv fond eng

Requisites of the project Bioengineering Rehabilitation for Wounded

PrivatBank for UAH transfers

Mykolaiv regional charitable foundation “BLAGOCHESTYA REGIONAL FUND”
PC CB PrivatBank
USREOU: 36143302
MFO: 326610
Account: 26004053210825
Purpose of payment: charity donation. Bioengineering rehabilitation for wounded

SWIFT-transfer in USD

Beneficiary: Mykolayiv Regional Charitable Foundation “Regional Foundation Blagochestya”
IBAN­code: UA803266100000026009053209659
Account: 26009053209659
Beneficiary address: UA 54000, Mykolaiv, Buznyka str. 5, 118
Beneficiary bank: Privatbank
50, Naberezhna Peremogy Street, Dnipropetrovsk, 49094, Ukraine
Swift code: PBANUA2X

Intermediary bank: JP Morgan Chase Bank,New York ,USA
Swift code: CHASUS33
Correspondent account: 001-­1­-000080
Description: Charitable donation for ‘Bioengineering rehabilitation for wounded’ project.
or
Intermediary bank: The Bank of New York Mellon, New York, USA
Swift code: IRVT US 3N
Correspondent account: 890-­0085-­754
Description: Charitable donation for ‘Bioengineering rehabilitation for wounded’ project.

SWIFT-transfer in EUR

Beneficiary: Mykolayiv Regional Charitable Foundation “Regional Foundation Blagochestya”
IBAN­code: UA413266100000026009053206287
Account: 26009053206287
Beneficiary address: UA 54000, Mykolaiv, Buznyka str. 5, 118
Beneficiary bank: Privatbank
50, Naberezhna Peremogy Street, Dnipropetrovsk, 49094, Ukraine
Swift code: PBANUA2X

Intermediary bank: Commerzbank AG ,Frankfurt am Main, Germany
Swift code: COBADEFF
Correspondent account: 400886700401
Description: Charitable donation for ‘Bioengineering rehabilitation for wounded’ project.


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